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Effect of polymorphisms in drug metabolism and transportation on plasma concentration of atorvastatin and its metabolites in patients with chronic kidney disease

Dyslipidemia due to renal insufficiency is a common complication in patients with chronic kidney diseases (CKD), and a major risk factor for the development of cardiovascular events. Atorvastatin (AT) is mainly used in the treatment of dyslipidemia in patients with CKD. However, response to the ator...

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Detalles Bibliográficos
Autores principales:	Jiang, Zebin, Wu, Zemin, Liu, Ruixue, Du, Qin, Fu, Xian, Li, Min, Kuang, Yongjun, Lin, Shen, Wu, Jiaxuan, Xie, Weiji, Shi, Ganggang, Peng, Yanqiang, Zheng, Fuchun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010391/ https://www.ncbi.nlm.nih.gov/pubmed/36923356 http://dx.doi.org/10.3389/fphar.2023.1102810

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