Cargando…
Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018
OBJECTIVE: Rheumatic diseases are associated with increased rates of hospitalized infection, but few studies have included Indigenous North American populations. Our objective was to evaluate the association of rheumatic disease diagnosis during a hospitalization with odds of hospitalized infections...
Autores principales: | , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wiley Periodicals, Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010486/ https://www.ncbi.nlm.nih.gov/pubmed/36683557 http://dx.doi.org/10.1002/acr2.11526 |
_version_ | 1784906182923649024 |
---|---|
author | Ferucci, Elizabeth D. Holck, Peter |
author_facet | Ferucci, Elizabeth D. Holck, Peter |
author_sort | Ferucci, Elizabeth D. |
collection | PubMed |
description | OBJECTIVE: Rheumatic diseases are associated with increased rates of hospitalized infection, but few studies have included Indigenous North American populations. Our objective was to evaluate the association of rheumatic disease diagnosis during a hospitalization with odds of hospitalized infections in Alaska and assess differences by race. METHODS: We used hospital discharge data from the Alaska Health Facilities Data Reporting Program from 2015 to 2018. We identified people with a rheumatic disease diagnosis based on any hospital discharge diagnosis of a set of rheumatic diseases and compared them to people hospitalized but without a rheumatic disease diagnosis. We determined odds of hospitalized infection by rheumatic disease diagnosis status and type, race, and type of infection. Using multivariable modeling, we determined factors associated with hospitalized infection. RESULTS: Having a rheumatic disease diagnosis other than osteoarthritis was associated with 1.90 higher odds of hospitalized infection overall, whereas people of Alaska Native/American Indian (AN/AI) race with rheumatic disease had 2.44 higher odds. The odds varied by rheumatic disease and were increased in all rheumatic diseases except osteoarthritis (0.73). The most common type of hospitalized infection was sepsis, but opportunistic infections and pneumonia were most associated with a rheumatic disease diagnosis. On multivariable analysis, having a rheumatic disease diagnosis other than osteoarthritis, being of older age, and being of AN/AI race were associated with increased odds of hospitalized infection, with an interaction between race and rheumatic disease status. CONCLUSION: This study confirmed the association of hospitalized infections with rheumatic disease diagnosis (other than osteoarthritis) during hospitalization and identified disparities by race. |
format | Online Article Text |
id | pubmed-10010486 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wiley Periodicals, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100104862023-03-14 Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 Ferucci, Elizabeth D. Holck, Peter ACR Open Rheumatol Original Article OBJECTIVE: Rheumatic diseases are associated with increased rates of hospitalized infection, but few studies have included Indigenous North American populations. Our objective was to evaluate the association of rheumatic disease diagnosis during a hospitalization with odds of hospitalized infections in Alaska and assess differences by race. METHODS: We used hospital discharge data from the Alaska Health Facilities Data Reporting Program from 2015 to 2018. We identified people with a rheumatic disease diagnosis based on any hospital discharge diagnosis of a set of rheumatic diseases and compared them to people hospitalized but without a rheumatic disease diagnosis. We determined odds of hospitalized infection by rheumatic disease diagnosis status and type, race, and type of infection. Using multivariable modeling, we determined factors associated with hospitalized infection. RESULTS: Having a rheumatic disease diagnosis other than osteoarthritis was associated with 1.90 higher odds of hospitalized infection overall, whereas people of Alaska Native/American Indian (AN/AI) race with rheumatic disease had 2.44 higher odds. The odds varied by rheumatic disease and were increased in all rheumatic diseases except osteoarthritis (0.73). The most common type of hospitalized infection was sepsis, but opportunistic infections and pneumonia were most associated with a rheumatic disease diagnosis. On multivariable analysis, having a rheumatic disease diagnosis other than osteoarthritis, being of older age, and being of AN/AI race were associated with increased odds of hospitalized infection, with an interaction between race and rheumatic disease status. CONCLUSION: This study confirmed the association of hospitalized infections with rheumatic disease diagnosis (other than osteoarthritis) during hospitalization and identified disparities by race. Wiley Periodicals, Inc. 2023-01-23 /pmc/articles/PMC10010486/ /pubmed/36683557 http://dx.doi.org/10.1002/acr2.11526 Text en © 2023 The Authors. ACR Open Rheumatology published by Wiley Periodicals LLC on behalf of American College of Rheumatology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Original Article Ferucci, Elizabeth D. Holck, Peter Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title | Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title_full | Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title_fullStr | Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title_full_unstemmed | Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title_short | Hospitalized Infections in Patients With Rheumatic Disease Hospitalizations in Alaska, 2015‐2018 |
title_sort | hospitalized infections in patients with rheumatic disease hospitalizations in alaska, 2015‐2018 |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010486/ https://www.ncbi.nlm.nih.gov/pubmed/36683557 http://dx.doi.org/10.1002/acr2.11526 |
work_keys_str_mv | AT feruccielizabethd hospitalizedinfectionsinpatientswithrheumaticdiseasehospitalizationsinalaska20152018 AT holckpeter hospitalizedinfectionsinpatientswithrheumaticdiseasehospitalizationsinalaska20152018 |