Cargando…

Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting

INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided...

Descripción completa

Detalles Bibliográficos
Autores principales: Yilmaz, Yucel, Kelesoglu, Saban, Elcik, Deniz, Ozmen, Rifat, Kalay, Nihat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010712/
https://www.ncbi.nlm.nih.gov/pubmed/35657307
http://dx.doi.org/10.21470/1678-9741-2021-0278
_version_ 1784906230521659392
author Yilmaz, Yucel
Kelesoglu, Saban
Elcik, Deniz
Ozmen, Rifat
Kalay, Nihat
author_facet Yilmaz, Yucel
Kelesoglu, Saban
Elcik, Deniz
Ozmen, Rifat
Kalay, Nihat
author_sort Yilmaz, Yucel
collection PubMed
description INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided the participants into two groups as those with and without new-onset atrial fibrillation. Prior to coronary artery bypass grafting, we evaluated blood samples, including systemic immune-inflammation index, and other laboratory parameters of the patients. We formulized the systemic immune-inflammation index score as platelet × neutrophil/lymphocyte counts. RESULTS: The findings revealed that new-onset atrial fibrillation occurred in 80 (20.4%) of 392 patients during follow-ups. Such patients had higher systemic immune-inflammation index, neutrophil/lymphocyte ratio, and C-reactive protein levels than those who did not develop new-onset atrial fibrillation (P<0.001, P<0.001, P=0.010, respectively). In receiver operating characteristic curve analysis, systemic immune-inflammation index levels > 712.8 predicted new-onset atrial fibrillation with a sensitivity of 85% and a specificity of 61.2% (area under the curve: 0.781, 95% confidence interval: 0.727-0.835; P<0.001). CONCLUSION: Overall, systemic immune-inflammation index, a novel inflammatory marker, may be used as a decisive marker to predict the development of atrial fibrillation following coronary artery bypass grafting.
format Online
Article
Text
id pubmed-10010712
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Sociedade Brasileira de Cirurgia Cardiovascular
record_format MEDLINE/PubMed
spelling pubmed-100107122023-03-14 Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting Yilmaz, Yucel Kelesoglu, Saban Elcik, Deniz Ozmen, Rifat Kalay, Nihat Braz J Cardiovasc Surg Original Article INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided the participants into two groups as those with and without new-onset atrial fibrillation. Prior to coronary artery bypass grafting, we evaluated blood samples, including systemic immune-inflammation index, and other laboratory parameters of the patients. We formulized the systemic immune-inflammation index score as platelet × neutrophil/lymphocyte counts. RESULTS: The findings revealed that new-onset atrial fibrillation occurred in 80 (20.4%) of 392 patients during follow-ups. Such patients had higher systemic immune-inflammation index, neutrophil/lymphocyte ratio, and C-reactive protein levels than those who did not develop new-onset atrial fibrillation (P<0.001, P<0.001, P=0.010, respectively). In receiver operating characteristic curve analysis, systemic immune-inflammation index levels > 712.8 predicted new-onset atrial fibrillation with a sensitivity of 85% and a specificity of 61.2% (area under the curve: 0.781, 95% confidence interval: 0.727-0.835; P<0.001). CONCLUSION: Overall, systemic immune-inflammation index, a novel inflammatory marker, may be used as a decisive marker to predict the development of atrial fibrillation following coronary artery bypass grafting. Sociedade Brasileira de Cirurgia Cardiovascular 2023 /pmc/articles/PMC10010712/ /pubmed/35657307 http://dx.doi.org/10.21470/1678-9741-2021-0278 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Yilmaz, Yucel
Kelesoglu, Saban
Elcik, Deniz
Ozmen, Rifat
Kalay, Nihat
Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title_full Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title_fullStr Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title_full_unstemmed Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title_short Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
title_sort predictive values of systemic immune-inflammation index in new-onset atrial fibrillation following coronary artery bypass grafting
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010712/
https://www.ncbi.nlm.nih.gov/pubmed/35657307
http://dx.doi.org/10.21470/1678-9741-2021-0278
work_keys_str_mv AT yilmazyucel predictivevaluesofsystemicimmuneinflammationindexinnewonsetatrialfibrillationfollowingcoronaryarterybypassgrafting
AT kelesoglusaban predictivevaluesofsystemicimmuneinflammationindexinnewonsetatrialfibrillationfollowingcoronaryarterybypassgrafting
AT elcikdeniz predictivevaluesofsystemicimmuneinflammationindexinnewonsetatrialfibrillationfollowingcoronaryarterybypassgrafting
AT ozmenrifat predictivevaluesofsystemicimmuneinflammationindexinnewonsetatrialfibrillationfollowingcoronaryarterybypassgrafting
AT kalaynihat predictivevaluesofsystemicimmuneinflammationindexinnewonsetatrialfibrillationfollowingcoronaryarterybypassgrafting