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Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting
INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cirurgia Cardiovascular
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010712/ https://www.ncbi.nlm.nih.gov/pubmed/35657307 http://dx.doi.org/10.21470/1678-9741-2021-0278 |
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author | Yilmaz, Yucel Kelesoglu, Saban Elcik, Deniz Ozmen, Rifat Kalay, Nihat |
author_facet | Yilmaz, Yucel Kelesoglu, Saban Elcik, Deniz Ozmen, Rifat Kalay, Nihat |
author_sort | Yilmaz, Yucel |
collection | PubMed |
description | INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided the participants into two groups as those with and without new-onset atrial fibrillation. Prior to coronary artery bypass grafting, we evaluated blood samples, including systemic immune-inflammation index, and other laboratory parameters of the patients. We formulized the systemic immune-inflammation index score as platelet × neutrophil/lymphocyte counts. RESULTS: The findings revealed that new-onset atrial fibrillation occurred in 80 (20.4%) of 392 patients during follow-ups. Such patients had higher systemic immune-inflammation index, neutrophil/lymphocyte ratio, and C-reactive protein levels than those who did not develop new-onset atrial fibrillation (P<0.001, P<0.001, P=0.010, respectively). In receiver operating characteristic curve analysis, systemic immune-inflammation index levels > 712.8 predicted new-onset atrial fibrillation with a sensitivity of 85% and a specificity of 61.2% (area under the curve: 0.781, 95% confidence interval: 0.727-0.835; P<0.001). CONCLUSION: Overall, systemic immune-inflammation index, a novel inflammatory marker, may be used as a decisive marker to predict the development of atrial fibrillation following coronary artery bypass grafting. |
format | Online Article Text |
id | pubmed-10010712 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Sociedade Brasileira de Cirurgia Cardiovascular |
record_format | MEDLINE/PubMed |
spelling | pubmed-100107122023-03-14 Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting Yilmaz, Yucel Kelesoglu, Saban Elcik, Deniz Ozmen, Rifat Kalay, Nihat Braz J Cardiovasc Surg Original Article INTRODUCTION: We investigated the relationship between the newly-defined systemic immune-inflammation index and the new-onset atrial fibrillation in patients undergoing coronary artery bypass grafting. METHOD: This study included 392 patients who underwent coronary artery bypass grafting. We divided the participants into two groups as those with and without new-onset atrial fibrillation. Prior to coronary artery bypass grafting, we evaluated blood samples, including systemic immune-inflammation index, and other laboratory parameters of the patients. We formulized the systemic immune-inflammation index score as platelet × neutrophil/lymphocyte counts. RESULTS: The findings revealed that new-onset atrial fibrillation occurred in 80 (20.4%) of 392 patients during follow-ups. Such patients had higher systemic immune-inflammation index, neutrophil/lymphocyte ratio, and C-reactive protein levels than those who did not develop new-onset atrial fibrillation (P<0.001, P<0.001, P=0.010, respectively). In receiver operating characteristic curve analysis, systemic immune-inflammation index levels > 712.8 predicted new-onset atrial fibrillation with a sensitivity of 85% and a specificity of 61.2% (area under the curve: 0.781, 95% confidence interval: 0.727-0.835; P<0.001). CONCLUSION: Overall, systemic immune-inflammation index, a novel inflammatory marker, may be used as a decisive marker to predict the development of atrial fibrillation following coronary artery bypass grafting. Sociedade Brasileira de Cirurgia Cardiovascular 2023 /pmc/articles/PMC10010712/ /pubmed/35657307 http://dx.doi.org/10.21470/1678-9741-2021-0278 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Yilmaz, Yucel Kelesoglu, Saban Elcik, Deniz Ozmen, Rifat Kalay, Nihat Predictive Values of Systemic Immune-Inflammation Index in New-Onset Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title | Predictive Values of Systemic Immune-Inflammation Index in New-Onset
Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title_full | Predictive Values of Systemic Immune-Inflammation Index in New-Onset
Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title_fullStr | Predictive Values of Systemic Immune-Inflammation Index in New-Onset
Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title_full_unstemmed | Predictive Values of Systemic Immune-Inflammation Index in New-Onset
Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title_short | Predictive Values of Systemic Immune-Inflammation Index in New-Onset
Atrial Fibrillation Following Coronary Artery Bypass Grafting |
title_sort | predictive values of systemic immune-inflammation index in new-onset
atrial fibrillation following coronary artery bypass grafting |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010712/ https://www.ncbi.nlm.nih.gov/pubmed/35657307 http://dx.doi.org/10.21470/1678-9741-2021-0278 |
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