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Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis
With the global burden of chronic liver disease (CLD) on the rise, especially due to the rise in obesity and metabolic syndrome, a third-world country like Nepal faces a different problem. With alcohol intake being rooted in Nepalese culture, alcoholic liver disease (ALD) is the most common cause of...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010787/ https://www.ncbi.nlm.nih.gov/pubmed/36923767 http://dx.doi.org/10.1097/MS9.0000000000000248 |
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author | Shrestha, Anish K. Shrestha, Anisha Shah, Sangam Bhandari, Aashna |
author_facet | Shrestha, Anish K. Shrestha, Anisha Shah, Sangam Bhandari, Aashna |
author_sort | Shrestha, Anish K. |
collection | PubMed |
description | With the global burden of chronic liver disease (CLD) on the rise, especially due to the rise in obesity and metabolic syndrome, a third-world country like Nepal faces a different problem. With alcohol intake being rooted in Nepalese culture, alcoholic liver disease (ALD) is the most common cause of CLD in our society. METHODS: This is a retrospective observational study conducted in the inpatient ward of the Department of Gastroenterology at the University in Nepal. Ethical approval was taken from the Institutional Review Committee, and a structured questionnaire format was used to record the data retrospectively using admission log books and admission sheets. Demographic data regarding age, sex, and address were collected, while the form of decompensation during presentation was used as a source of clinical data. For statistical analysis, see SPSS 21 (IBM Corp., Released 2012. IBM SPSS Statistics for Windows, Version 21.0; IBM Corp.) was used. RESULTS: A male-to-female ratio of 2:1 was found, with ALD the most common cause of CLD in admitted patients. Similarly, the majority of patients were admitted due to ascites, which was compounded by spontaneous bacterial peritonitis. 93.60% of patients admitted with CLD had a deranged prothrombin time, while only about a third of patients had elevated aspartate aminotransferase and/or alanine aminotransferase. CONCLUSION: The large burden of ALD highlights the importance of awareness programs at the community level, which have been neglected till date. |
format | Online Article Text |
id | pubmed-10010787 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-100107872023-03-14 Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis Shrestha, Anish K. Shrestha, Anisha Shah, Sangam Bhandari, Aashna Ann Med Surg (Lond) Original Research With the global burden of chronic liver disease (CLD) on the rise, especially due to the rise in obesity and metabolic syndrome, a third-world country like Nepal faces a different problem. With alcohol intake being rooted in Nepalese culture, alcoholic liver disease (ALD) is the most common cause of CLD in our society. METHODS: This is a retrospective observational study conducted in the inpatient ward of the Department of Gastroenterology at the University in Nepal. Ethical approval was taken from the Institutional Review Committee, and a structured questionnaire format was used to record the data retrospectively using admission log books and admission sheets. Demographic data regarding age, sex, and address were collected, while the form of decompensation during presentation was used as a source of clinical data. For statistical analysis, see SPSS 21 (IBM Corp., Released 2012. IBM SPSS Statistics for Windows, Version 21.0; IBM Corp.) was used. RESULTS: A male-to-female ratio of 2:1 was found, with ALD the most common cause of CLD in admitted patients. Similarly, the majority of patients were admitted due to ascites, which was compounded by spontaneous bacterial peritonitis. 93.60% of patients admitted with CLD had a deranged prothrombin time, while only about a third of patients had elevated aspartate aminotransferase and/or alanine aminotransferase. CONCLUSION: The large burden of ALD highlights the importance of awareness programs at the community level, which have been neglected till date. Lippincott Williams & Wilkins 2023-02-17 /pmc/articles/PMC10010787/ /pubmed/36923767 http://dx.doi.org/10.1097/MS9.0000000000000248 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (https://creativecommons.org/licenses/by/4.0/) (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Original Research Shrestha, Anish K. Shrestha, Anisha Shah, Sangam Bhandari, Aashna Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title | Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title_full | Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title_fullStr | Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title_full_unstemmed | Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title_short | Clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
title_sort | clinicodemographic profile of chronic liver disease patients at a tertiary care hospital: a retrospective analysis |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10010787/ https://www.ncbi.nlm.nih.gov/pubmed/36923767 http://dx.doi.org/10.1097/MS9.0000000000000248 |
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