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Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective
INTRODUCTION: Epidermoid cysts are rare benign lesions of the central nervous system which accounts for approximately 1–2 % of all intracranial tumours. They are commonly located in the parasellar region, cerebellopontine angle; however, brain parenchyma origin is rare. We report clinicopathological...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011047/ https://www.ncbi.nlm.nih.gov/pubmed/36913889 http://dx.doi.org/10.1016/j.ijscr.2023.107969 |
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author | Khaba, Moshawa Calvin Dube, Nomthandazo Amanda |
author_facet | Khaba, Moshawa Calvin Dube, Nomthandazo Amanda |
author_sort | Khaba, Moshawa Calvin |
collection | PubMed |
description | INTRODUCTION: Epidermoid cysts are rare benign lesions of the central nervous system which accounts for approximately 1–2 % of all intracranial tumours. They are commonly located in the parasellar region, cerebellopontine angle; however, brain parenchyma origin is rare. We report clinicopathological features of these rare lesions. METHOD AND MATERIAL: This is a retrospective study of epidermoid cyst of the brain diagnosed between 01 January 2014 and 31 December 2020. RESULTS: The four patients had mean age of 30,8 years (range: 3–63), one male and 3 females. All four patients presented with headache and one associated with seizures. Radiological images showed two posterior fossa; each occipital and temporal locations. All tumours were successfully removed and histopathological assessment confirmed epidermoid cysts. All patients showed clinical improvement and were discharged home. CONCLUSION: Epidermoid cysts of the brain are rare and still remain a preoperative clinico-radiological conundrum as they may be indistinguishable from other intracranial tumours. Therefore, collaboration with histopathologists is advised in the management of these cases. |
format | Online Article Text |
id | pubmed-10011047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-100110472023-03-15 Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective Khaba, Moshawa Calvin Dube, Nomthandazo Amanda Int J Surg Case Rep Case Series INTRODUCTION: Epidermoid cysts are rare benign lesions of the central nervous system which accounts for approximately 1–2 % of all intracranial tumours. They are commonly located in the parasellar region, cerebellopontine angle; however, brain parenchyma origin is rare. We report clinicopathological features of these rare lesions. METHOD AND MATERIAL: This is a retrospective study of epidermoid cyst of the brain diagnosed between 01 January 2014 and 31 December 2020. RESULTS: The four patients had mean age of 30,8 years (range: 3–63), one male and 3 females. All four patients presented with headache and one associated with seizures. Radiological images showed two posterior fossa; each occipital and temporal locations. All tumours were successfully removed and histopathological assessment confirmed epidermoid cysts. All patients showed clinical improvement and were discharged home. CONCLUSION: Epidermoid cysts of the brain are rare and still remain a preoperative clinico-radiological conundrum as they may be indistinguishable from other intracranial tumours. Therefore, collaboration with histopathologists is advised in the management of these cases. Elsevier 2023-03-10 /pmc/articles/PMC10011047/ /pubmed/36913889 http://dx.doi.org/10.1016/j.ijscr.2023.107969 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Series Khaba, Moshawa Calvin Dube, Nomthandazo Amanda Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title | Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title_full | Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title_fullStr | Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title_full_unstemmed | Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title_short | Clinicopathological report on epidermoid cysts of the brain: A case series and literature review from an African perspective |
title_sort | clinicopathological report on epidermoid cysts of the brain: a case series and literature review from an african perspective |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011047/ https://www.ncbi.nlm.nih.gov/pubmed/36913889 http://dx.doi.org/10.1016/j.ijscr.2023.107969 |
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