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Mitochondrial respiration reduces exposure of the nucleus to oxygen
The endosymbiotic theory posits that ancient eukaryotic cells engulfed O(2)-consuming prokaryotes, which protected them against O(2) toxicity. Previous studies have shown that cells lacking cytochrome c oxidase (COX), required for respiration, have increased DNA damage and reduced proliferation, whi...
Autores principales: | Mori, Mateus Prates, Penjweini, Rozhin, Ma, Jin, Alspaugh, Greg, Andreoni, Alessio, Kim, Young-Chae, Wang, Ping-yuan, Knutson, Jay R., Hwang, Paul M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011062/ https://www.ncbi.nlm.nih.gov/pubmed/36796514 http://dx.doi.org/10.1016/j.jbc.2023.103018 |
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