Histone acetyltransferase KAT2A modulates neural stem cell differentiation and proliferation by inducing degradation of the transcription factor PAX6

Neural stem cells (NSCs) proliferation and differentiation rely on proper expression and posttranslational modification of transcription factors involved in the determination of cell fate. Further characterization is needed to connect modifying enzymes with their transcription factor substrates in t...

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Detalles Bibliográficos
Autores principales: Dong, Zhangji, He, Wei, Lin, Ge, Chen, Xu, Cao, Sixian, Guan, Tuchen, Sun, Ying, Zhang, Yufang, Qi, Mengwei, Guo, Beibei, Zhou, Zhihao, Zhuo, Run, Wu, Ronghua, Liu, Mei, Liu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011063/
https://www.ncbi.nlm.nih.gov/pubmed/36791914
http://dx.doi.org/10.1016/j.jbc.2023.103020

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