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Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas

PURPOSE: A palatal fistula following the closure of palatal clefts remains a difficult clinical complication. Surgical treatment of fistulas is often complicated, with high recurrence rates. We present our results of fistula closure augmented with GTR, a resorbable membrane designed to promote guide...

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Autores principales: Wang, Yufeng, Yang, Fangling, Liu, Weilong, Fan, Xiaofen, Lu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011083/
https://www.ncbi.nlm.nih.gov/pubmed/36925507
http://dx.doi.org/10.3389/fsurg.2023.1134934
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author Wang, Yufeng
Yang, Fangling
Liu, Weilong
Fan, Xiaofen
Lu, Yong
author_facet Wang, Yufeng
Yang, Fangling
Liu, Weilong
Fan, Xiaofen
Lu, Yong
author_sort Wang, Yufeng
collection PubMed
description PURPOSE: A palatal fistula following the closure of palatal clefts remains a difficult clinical complication. Surgical treatment of fistulas is often complicated, with high recurrence rates. We present our results of fistula closure augmented with GTR, a resorbable membrane designed to promote guided tissue regeneration. METHODS: We reviewed the records of 75 patients operated on between 2008 and 2022 for closure of the palatal fistula. The patients included 24 who underwent fistula closure augmented with GTR and 51 who underwent fistula closure with other techniques. We reviewed the age at surgery, sex, fistula location, and outcome. Operation success was defined as an asymptomatic patient with a healed fistula on clinical examination. RESULTS: The overall fistula closure rate was 79.1% in the GTR group and 76.5% in the non-GTR group(p = 0.79). DISCUSSION: The success rate of fistula closure in the GTR group is comparable to that in the non-GTR group in this study. An additional advantage is that this procedure does not require harvesting any autologous tissue and reduces tissue damage in the long term.
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spelling pubmed-100110832023-03-15 Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas Wang, Yufeng Yang, Fangling Liu, Weilong Fan, Xiaofen Lu, Yong Front Surg Surgery PURPOSE: A palatal fistula following the closure of palatal clefts remains a difficult clinical complication. Surgical treatment of fistulas is often complicated, with high recurrence rates. We present our results of fistula closure augmented with GTR, a resorbable membrane designed to promote guided tissue regeneration. METHODS: We reviewed the records of 75 patients operated on between 2008 and 2022 for closure of the palatal fistula. The patients included 24 who underwent fistula closure augmented with GTR and 51 who underwent fistula closure with other techniques. We reviewed the age at surgery, sex, fistula location, and outcome. Operation success was defined as an asymptomatic patient with a healed fistula on clinical examination. RESULTS: The overall fistula closure rate was 79.1% in the GTR group and 76.5% in the non-GTR group(p = 0.79). DISCUSSION: The success rate of fistula closure in the GTR group is comparable to that in the non-GTR group in this study. An additional advantage is that this procedure does not require harvesting any autologous tissue and reduces tissue damage in the long term. Frontiers Media S.A. 2023-02-28 /pmc/articles/PMC10011083/ /pubmed/36925507 http://dx.doi.org/10.3389/fsurg.2023.1134934 Text en © 2023 Wang, Yang, Liu, Fan and Lu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Wang, Yufeng
Yang, Fangling
Liu, Weilong
Fan, Xiaofen
Lu, Yong
Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title_full Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title_fullStr Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title_full_unstemmed Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title_short Evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
title_sort evaluation of the effect of a resorbable membrane on the closure of palatal fistulas
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011083/
https://www.ncbi.nlm.nih.gov/pubmed/36925507
http://dx.doi.org/10.3389/fsurg.2023.1134934
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