Notch-Jagged1 signaling and response to bevacizumab therapy in advanced colorectal cancer: A glance to radiomics or back to physiopathology?

INTRODUCTION: The Notch intracellular domain (NICD) and its ligands Jagged-1(Jag1), Delta-like ligand (DLL-3) and DLL4 play an important role in neoangiogenesis. Previous studies suggest a correlation between the tissue levels of NICD and response to therapy with bevacizumab in colorectal cancer (CR...

Descripción completa

Detalles Bibliográficos
Autores principales: Negri, Francesca, Bottarelli, Lorena, Pedrazzi, Giuseppe, Maddalo, Michele, Leo, Ludovica, Milanese, Gianluca, Sala, Roberto, Lecchini, Michele, Campanini, Nicoletta, Bozzetti, Cecilia, Zavani, Andrea, Di Rienzo, Gianluca, Azzoni, Cinzia, Silini, Enrico Maria, Sverzellati, Nicola, Gaiani, Federica, de’ Angelis, Gian Luigi, Gnetti, Letizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011088/
https://www.ncbi.nlm.nih.gov/pubmed/36925919
http://dx.doi.org/10.3389/fonc.2023.1132564

Ejemplares similares

Ejemplares similares