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Obesity and renal disease: Benefits of bariatric surgery
The prevalence of obesity, a preventable and reversible condition with a high impact on health, continues to rise, especially after the COVID-19 pandemic. Severe overweight is well recognized as a risk factor for diabetes and hypertension, among other conditions, that may increase cardiovascular ris...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011092/ https://www.ncbi.nlm.nih.gov/pubmed/36926320 http://dx.doi.org/10.3389/fmed.2023.1134644 |
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author | Ardiles, Leopoldo G. |
author_facet | Ardiles, Leopoldo G. |
author_sort | Ardiles, Leopoldo G. |
collection | PubMed |
description | The prevalence of obesity, a preventable and reversible condition with a high impact on health, continues to rise, especially after the COVID-19 pandemic. Severe overweight is well recognized as a risk factor for diabetes and hypertension, among other conditions, that may increase cardiovascular risk. Obesity has grown simultaneously with a rise in the prevalence of chronic kidney disease, and a pathophysiological link has been established, which explains its role in generating the conditions to facilitate the emergence and maximize the impact of the risk factors of chronic kidney disease and its progression to more advanced stages. Knowing the mechanisms involved and having different tools to reverse the overweight and its consequences, bariatric surgery has arisen as a useful and efficient method, complementary or alternative to others, such as lifestyle changes and/or pharmacotherapy. In a detailed review, the mechanisms involved in the renal consequences of obesity, the impact on risk factors, and the potential benefit of bariatric surgery at different stages of the disease and its progression are exposed and analyzed. Although the observational evidence supports the value of bariatric surgery as a renoprotective measure in individuals with obesity, diabetic or not, randomized studies are expected to establish evidence-based recommendations that demonstrate its positive risk–benefit balance as a complementary or alternative therapeutic tool. |
format | Online Article Text |
id | pubmed-10011092 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100110922023-03-15 Obesity and renal disease: Benefits of bariatric surgery Ardiles, Leopoldo G. Front Med (Lausanne) Medicine The prevalence of obesity, a preventable and reversible condition with a high impact on health, continues to rise, especially after the COVID-19 pandemic. Severe overweight is well recognized as a risk factor for diabetes and hypertension, among other conditions, that may increase cardiovascular risk. Obesity has grown simultaneously with a rise in the prevalence of chronic kidney disease, and a pathophysiological link has been established, which explains its role in generating the conditions to facilitate the emergence and maximize the impact of the risk factors of chronic kidney disease and its progression to more advanced stages. Knowing the mechanisms involved and having different tools to reverse the overweight and its consequences, bariatric surgery has arisen as a useful and efficient method, complementary or alternative to others, such as lifestyle changes and/or pharmacotherapy. In a detailed review, the mechanisms involved in the renal consequences of obesity, the impact on risk factors, and the potential benefit of bariatric surgery at different stages of the disease and its progression are exposed and analyzed. Although the observational evidence supports the value of bariatric surgery as a renoprotective measure in individuals with obesity, diabetic or not, randomized studies are expected to establish evidence-based recommendations that demonstrate its positive risk–benefit balance as a complementary or alternative therapeutic tool. Frontiers Media S.A. 2023-02-28 /pmc/articles/PMC10011092/ /pubmed/36926320 http://dx.doi.org/10.3389/fmed.2023.1134644 Text en Copyright © 2023 Ardiles. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Ardiles, Leopoldo G. Obesity and renal disease: Benefits of bariatric surgery |
title | Obesity and renal disease: Benefits of bariatric surgery |
title_full | Obesity and renal disease: Benefits of bariatric surgery |
title_fullStr | Obesity and renal disease: Benefits of bariatric surgery |
title_full_unstemmed | Obesity and renal disease: Benefits of bariatric surgery |
title_short | Obesity and renal disease: Benefits of bariatric surgery |
title_sort | obesity and renal disease: benefits of bariatric surgery |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011092/ https://www.ncbi.nlm.nih.gov/pubmed/36926320 http://dx.doi.org/10.3389/fmed.2023.1134644 |
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