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cGAS-STING pathway as a potential trigger of immunosenescence and inflammaging

Aging is associated with an increased incidence of autoimmune diseases, despite the progressive decline of immune responses (immunosenescence). This apparent paradox can be explained by the age-related chronic low-grade systemic inflammation (inflammaging) and progressive dysregulation of innate sig...

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Detalles Bibliográficos
Autores principales: Schmitz, Carine Raquel Richter, Maurmann, Rafael Moura, Guma, Fatima T. C. R., Bauer, Moisés Evandro, Barbé-Tuana, Florencia Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011111/
https://www.ncbi.nlm.nih.gov/pubmed/36926349
http://dx.doi.org/10.3389/fimmu.2023.1132653