Cargando…
The current regenerative medicine approaches of craniofacial diseases: A narrative review
Craniofacial deformities (CFDs) develop following oncological resection, trauma, or congenital disorders. Trauma is one of the top five causes of death globally, with rates varying from country to country. They result in a non-healing composite tissue wound as they degenerate in soft or hard tissues...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011176/ https://www.ncbi.nlm.nih.gov/pubmed/36926524 http://dx.doi.org/10.3389/fcell.2023.1112378 |
_version_ | 1784906331903229952 |
---|---|
author | Tahmasebi, Elahe Mohammadi, Mehdi Alam, Mostafa Abbasi, Kamyar Gharibian Bajestani, Saeed Khanmohammad, Rojin Haseli, Mohsen Yazdanian, Mohsen Esmaeili Fard Barzegar, Peyman Tebyaniyan, Hamid |
author_facet | Tahmasebi, Elahe Mohammadi, Mehdi Alam, Mostafa Abbasi, Kamyar Gharibian Bajestani, Saeed Khanmohammad, Rojin Haseli, Mohsen Yazdanian, Mohsen Esmaeili Fard Barzegar, Peyman Tebyaniyan, Hamid |
author_sort | Tahmasebi, Elahe |
collection | PubMed |
description | Craniofacial deformities (CFDs) develop following oncological resection, trauma, or congenital disorders. Trauma is one of the top five causes of death globally, with rates varying from country to country. They result in a non-healing composite tissue wound as they degenerate in soft or hard tissues. Approximately one-third of oral diseases are caused by gum disease. Due to the complexity of anatomical structures in the region and the variety of tissue-specific requirements, CFD treatments present many challenges. Many treatment methods for CFDs are available today, such as drugs, regenerative medicine (RM), surgery, and tissue engineering. Functional restoration of a tissue or an organ after trauma or other chronic diseases is the focus of this emerging field of science. The materials and methodologies used in craniofacial reconstruction have significantly improved in the last few years. A facial fracture requires bone preservation as much as possible, so tiny fragments are removed initially. It is possible to replace bone marrow stem cells with oral stem cells for CFDs due to their excellent potential for bone formation. This review article discusses regenerative approaches for different types of craniofacial diseases. |
format | Online Article Text |
id | pubmed-10011176 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100111762023-03-15 The current regenerative medicine approaches of craniofacial diseases: A narrative review Tahmasebi, Elahe Mohammadi, Mehdi Alam, Mostafa Abbasi, Kamyar Gharibian Bajestani, Saeed Khanmohammad, Rojin Haseli, Mohsen Yazdanian, Mohsen Esmaeili Fard Barzegar, Peyman Tebyaniyan, Hamid Front Cell Dev Biol Cell and Developmental Biology Craniofacial deformities (CFDs) develop following oncological resection, trauma, or congenital disorders. Trauma is one of the top five causes of death globally, with rates varying from country to country. They result in a non-healing composite tissue wound as they degenerate in soft or hard tissues. Approximately one-third of oral diseases are caused by gum disease. Due to the complexity of anatomical structures in the region and the variety of tissue-specific requirements, CFD treatments present many challenges. Many treatment methods for CFDs are available today, such as drugs, regenerative medicine (RM), surgery, and tissue engineering. Functional restoration of a tissue or an organ after trauma or other chronic diseases is the focus of this emerging field of science. The materials and methodologies used in craniofacial reconstruction have significantly improved in the last few years. A facial fracture requires bone preservation as much as possible, so tiny fragments are removed initially. It is possible to replace bone marrow stem cells with oral stem cells for CFDs due to their excellent potential for bone formation. This review article discusses regenerative approaches for different types of craniofacial diseases. Frontiers Media S.A. 2023-02-28 /pmc/articles/PMC10011176/ /pubmed/36926524 http://dx.doi.org/10.3389/fcell.2023.1112378 Text en Copyright © 2023 Tahmasebi, Mohammadi, Alam, Abbasi, Gharibian Bajestani, Khanmohammad, Haseli, Yazdanian, Esmaeili Fard Barzegar and Tebyaniyan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cell and Developmental Biology Tahmasebi, Elahe Mohammadi, Mehdi Alam, Mostafa Abbasi, Kamyar Gharibian Bajestani, Saeed Khanmohammad, Rojin Haseli, Mohsen Yazdanian, Mohsen Esmaeili Fard Barzegar, Peyman Tebyaniyan, Hamid The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title | The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title_full | The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title_fullStr | The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title_full_unstemmed | The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title_short | The current regenerative medicine approaches of craniofacial diseases: A narrative review |
title_sort | current regenerative medicine approaches of craniofacial diseases: a narrative review |
topic | Cell and Developmental Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011176/ https://www.ncbi.nlm.nih.gov/pubmed/36926524 http://dx.doi.org/10.3389/fcell.2023.1112378 |
work_keys_str_mv | AT tahmasebielahe thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT mohammadimehdi thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT alammostafa thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT abbasikamyar thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT gharibianbajestanisaeed thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT khanmohammadrojin thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT haselimohsen thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT yazdanianmohsen thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT esmaeilifardbarzegarpeyman thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT tebyaniyanhamid thecurrentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT tahmasebielahe currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT mohammadimehdi currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT alammostafa currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT abbasikamyar currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT gharibianbajestanisaeed currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT khanmohammadrojin currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT haselimohsen currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT yazdanianmohsen currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT esmaeilifardbarzegarpeyman currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview AT tebyaniyanhamid currentregenerativemedicineapproachesofcraniofacialdiseasesanarrativereview |