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An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report

Guillain-Barré syndrome (GBS) is an autoimmune neurological disorder with unknown aetiology. Given the incidence of GBS is between 1.2 and 1.9 cases per 100,000 people annually [1], it is extremely rare in pregnancy. We report a case with a challenging diagnosis of pre-eclampsia (PET) in a 34-year-o...

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Autores principales: Wang, Jue, Bahabri, Amin, Wong, Patricia, Anantharachagan, Arisudhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011183/
https://www.ncbi.nlm.nih.gov/pubmed/36926548
http://dx.doi.org/10.1016/j.crwh.2023.e00489
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author Wang, Jue
Bahabri, Amin
Wong, Patricia
Anantharachagan, Arisudhan
author_facet Wang, Jue
Bahabri, Amin
Wong, Patricia
Anantharachagan, Arisudhan
author_sort Wang, Jue
collection PubMed
description Guillain-Barré syndrome (GBS) is an autoimmune neurological disorder with unknown aetiology. Given the incidence of GBS is between 1.2 and 1.9 cases per 100,000 people annually [1], it is extremely rare in pregnancy. We report a case with a challenging diagnosis of pre-eclampsia (PET) in a 34-year-old diabetic primigravida who was diagnosed with GBS at 30 weeks of gestation. At her initial presentation, she complained of progressive weakness of her limbs and facial muscles. This was associated with difficulty swallowing. The diagnosis of GBS was made based on electromyography (EMG) and clinical findings. She was managed conservatively with supportive management and was delivered by lower segment caesarean section at 34 weeks of gestation due to rapidly deteriorating liver function tests (LFTs) in the likely setting of PET.
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spelling pubmed-100111832023-03-15 An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report Wang, Jue Bahabri, Amin Wong, Patricia Anantharachagan, Arisudhan Case Rep Womens Health Article Guillain-Barré syndrome (GBS) is an autoimmune neurological disorder with unknown aetiology. Given the incidence of GBS is between 1.2 and 1.9 cases per 100,000 people annually [1], it is extremely rare in pregnancy. We report a case with a challenging diagnosis of pre-eclampsia (PET) in a 34-year-old diabetic primigravida who was diagnosed with GBS at 30 weeks of gestation. At her initial presentation, she complained of progressive weakness of her limbs and facial muscles. This was associated with difficulty swallowing. The diagnosis of GBS was made based on electromyography (EMG) and clinical findings. She was managed conservatively with supportive management and was delivered by lower segment caesarean section at 34 weeks of gestation due to rapidly deteriorating liver function tests (LFTs) in the likely setting of PET. Elsevier 2023-03-01 /pmc/articles/PMC10011183/ /pubmed/36926548 http://dx.doi.org/10.1016/j.crwh.2023.e00489 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Wang, Jue
Bahabri, Amin
Wong, Patricia
Anantharachagan, Arisudhan
An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title_full An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title_fullStr An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title_full_unstemmed An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title_short An atypical presentation of pre-eclampsia (PET) in a patient diagnosed with Guillain-Barré syndrome: A case report
title_sort atypical presentation of pre-eclampsia (pet) in a patient diagnosed with guillain-barré syndrome: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011183/
https://www.ncbi.nlm.nih.gov/pubmed/36926548
http://dx.doi.org/10.1016/j.crwh.2023.e00489
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