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Dantrolene improves left ventricular diastolic property in mineralcorticoid-salt-induced hypertensive rats
Left ventricular (LV) diastolic dysfunction is increasingly common in heart failure with preserved ejection fraction (HFpEF), and new drug therapy is desired. We recently reported that dantrolene (DAN) attenuates pressure-overload induced hypertrophic signaling through stabilization of tetrameric st...
Autores principales: | Nawata, Junya, Yamamoto, Takeshi, Tanaka, Shinji, Yano, Yasutake, Uchida, Tomoyuki, Fujii, Shohei, Nakamura, Yoshihide, Suetomi, Takeshi, Uchinoumi, Hitoshi, Oda, Tetsuro, Kobayashi, Shigeki, Yano, Masafumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011190/ https://www.ncbi.nlm.nih.gov/pubmed/36926278 http://dx.doi.org/10.1016/j.bbrep.2023.101449 |
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