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Dantrolene improves left ventricular diastolic property in mineralcorticoid-salt-induced hypertensive rats

Left ventricular (LV) diastolic dysfunction is increasingly common in heart failure with preserved ejection fraction (HFpEF), and new drug therapy is desired. We recently reported that dantrolene (DAN) attenuates pressure-overload induced hypertrophic signaling through stabilization of tetrameric st...

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Detalles Bibliográficos
Autores principales: Nawata, Junya, Yamamoto, Takeshi, Tanaka, Shinji, Yano, Yasutake, Uchida, Tomoyuki, Fujii, Shohei, Nakamura, Yoshihide, Suetomi, Takeshi, Uchinoumi, Hitoshi, Oda, Tetsuro, Kobayashi, Shigeki, Yano, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011190/
https://www.ncbi.nlm.nih.gov/pubmed/36926278
http://dx.doi.org/10.1016/j.bbrep.2023.101449

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