Cargando…

Biometric Risk Factors for Central Serous Chorioretinopathy

INTRODUCTION: Central serous chorioretinopathy (CSCR) is a common disease that in chronic form can lead to significant visual impairment. Hence, the systemic and local risk factors of CSCR have been analyzed to possibly prevent its onset. The goal of the present study was to find the biometric param...

Descripción completa

Detalles Bibliográficos
Autores principales: Gawęcki, Maciej, Grzybowski, Andrzej, Święch, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011280/
https://www.ncbi.nlm.nih.gov/pubmed/36840908
http://dx.doi.org/10.1007/s40123-023-00687-z
_version_ 1784906355050545152
author Gawęcki, Maciej
Grzybowski, Andrzej
Święch, Anna
author_facet Gawęcki, Maciej
Grzybowski, Andrzej
Święch, Anna
author_sort Gawęcki, Maciej
collection PubMed
description INTRODUCTION: Central serous chorioretinopathy (CSCR) is a common disease that in chronic form can lead to significant visual impairment. Hence, the systemic and local risk factors of CSCR have been analyzed to possibly prevent its onset. The goal of the present study was to find the biometric parameters characteristic for CSCR. METHODS: The study included 66 eyes of 60 consecutive patients who were diagnosed with acute or chronic CSCR between January 01 2021 and June 30 2021. There were 46 males and 14 females with a mean age of 48.8 ± 10.0 years in the study cohort. Six patients had symptomatic binocular disease. The axial length and retinal parameters of all patients were measured with spectral domain optical coherence tomography (SD-OCT), and refraction error was tested after cycloplegia. The results of the affected eyes were compared with those of healthy fellow eyes (with exclusion of eyes previously affected by CSCR or with any other ocular disorder) (39 eyes) and the control group (75 eyes), and correlated to the duration of the disease. RESULTS: No significant differences were revealed in axial length between the affected eyes, healthy fellow eyes, and controls (23.31 ± 1.06 mm versus 23.59 ± 1.20 mm versus 23.33 ± 1.19 mm, respectively). The distribution of refraction errors was similar in the three analyzed groups. A hypermetropic shift was noted in the affected eyes versus controls (p = 0.030); however, no difference was noted in refraction error between the healthy fellow CSCR eyes and controls (p = 0.418). Both acute and chronic CSCR cases, as well as their fellow eyes, demonstrated significantly greater choroidal thickness compared with healthy individuals (p < 0.001). Longer disease duration was correlated with a significant deficit in macular volume and average central retinal thickness (p < 0.05). CONCLUSIONS: CSCR is a clinical entity that can occur in patients with every type of refraction error. A shorter axial length of the eyeball is not associated with the diagnosis of CSCR; however, increased choroidal thickness is typical of this entity. Longer disease duration is correlated with the loss of retinal thickness and volume.
format Online
Article
Text
id pubmed-10011280
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Springer Healthcare
record_format MEDLINE/PubMed
spelling pubmed-100112802023-03-15 Biometric Risk Factors for Central Serous Chorioretinopathy Gawęcki, Maciej Grzybowski, Andrzej Święch, Anna Ophthalmol Ther Original Research INTRODUCTION: Central serous chorioretinopathy (CSCR) is a common disease that in chronic form can lead to significant visual impairment. Hence, the systemic and local risk factors of CSCR have been analyzed to possibly prevent its onset. The goal of the present study was to find the biometric parameters characteristic for CSCR. METHODS: The study included 66 eyes of 60 consecutive patients who were diagnosed with acute or chronic CSCR between January 01 2021 and June 30 2021. There were 46 males and 14 females with a mean age of 48.8 ± 10.0 years in the study cohort. Six patients had symptomatic binocular disease. The axial length and retinal parameters of all patients were measured with spectral domain optical coherence tomography (SD-OCT), and refraction error was tested after cycloplegia. The results of the affected eyes were compared with those of healthy fellow eyes (with exclusion of eyes previously affected by CSCR or with any other ocular disorder) (39 eyes) and the control group (75 eyes), and correlated to the duration of the disease. RESULTS: No significant differences were revealed in axial length between the affected eyes, healthy fellow eyes, and controls (23.31 ± 1.06 mm versus 23.59 ± 1.20 mm versus 23.33 ± 1.19 mm, respectively). The distribution of refraction errors was similar in the three analyzed groups. A hypermetropic shift was noted in the affected eyes versus controls (p = 0.030); however, no difference was noted in refraction error between the healthy fellow CSCR eyes and controls (p = 0.418). Both acute and chronic CSCR cases, as well as their fellow eyes, demonstrated significantly greater choroidal thickness compared with healthy individuals (p < 0.001). Longer disease duration was correlated with a significant deficit in macular volume and average central retinal thickness (p < 0.05). CONCLUSIONS: CSCR is a clinical entity that can occur in patients with every type of refraction error. A shorter axial length of the eyeball is not associated with the diagnosis of CSCR; however, increased choroidal thickness is typical of this entity. Longer disease duration is correlated with the loss of retinal thickness and volume. Springer Healthcare 2023-02-25 2023-04 /pmc/articles/PMC10011280/ /pubmed/36840908 http://dx.doi.org/10.1007/s40123-023-00687-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research
Gawęcki, Maciej
Grzybowski, Andrzej
Święch, Anna
Biometric Risk Factors for Central Serous Chorioretinopathy
title Biometric Risk Factors for Central Serous Chorioretinopathy
title_full Biometric Risk Factors for Central Serous Chorioretinopathy
title_fullStr Biometric Risk Factors for Central Serous Chorioretinopathy
title_full_unstemmed Biometric Risk Factors for Central Serous Chorioretinopathy
title_short Biometric Risk Factors for Central Serous Chorioretinopathy
title_sort biometric risk factors for central serous chorioretinopathy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011280/
https://www.ncbi.nlm.nih.gov/pubmed/36840908
http://dx.doi.org/10.1007/s40123-023-00687-z
work_keys_str_mv AT gaweckimaciej biometricriskfactorsforcentralserouschorioretinopathy
AT grzybowskiandrzej biometricriskfactorsforcentralserouschorioretinopathy
AT swiechanna biometricriskfactorsforcentralserouschorioretinopathy