Cargando…

Astrocytes as metabolic suppliers to support neuronal activity and brain functions

Energy metabolism is essential for brain function. In recent years, lactate shuttling between astrocytes and neurons has become a fundamental concept of neuroenergetics. However, it remains unclear to what extent this process is critical for different aspects of cognition, their underlying mechanism...

Descripción completa

Detalles Bibliográficos
Autores principales: Roumes, Hélène, Pellerin, Luc, Bouzier-Sore, Anne-Karine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011397/
https://www.ncbi.nlm.nih.gov/pubmed/36504117
http://dx.doi.org/10.1042/EBC20220080
_version_ 1784906383776284672
author Roumes, Hélène
Pellerin, Luc
Bouzier-Sore, Anne-Karine
author_facet Roumes, Hélène
Pellerin, Luc
Bouzier-Sore, Anne-Karine
author_sort Roumes, Hélène
collection PubMed
description Energy metabolism is essential for brain function. In recent years, lactate shuttling between astrocytes and neurons has become a fundamental concept of neuroenergetics. However, it remains unclear to what extent this process is critical for different aspects of cognition, their underlying mechanisms, as well as for the signals used to monitor brain activation.
format Online
Article
Text
id pubmed-10011397
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Portland Press Ltd.
record_format MEDLINE/PubMed
spelling pubmed-100113972023-03-15 Astrocytes as metabolic suppliers to support neuronal activity and brain functions Roumes, Hélène Pellerin, Luc Bouzier-Sore, Anne-Karine Essays Biochem Neuroscience Energy metabolism is essential for brain function. In recent years, lactate shuttling between astrocytes and neurons has become a fundamental concept of neuroenergetics. However, it remains unclear to what extent this process is critical for different aspects of cognition, their underlying mechanisms, as well as for the signals used to monitor brain activation. Portland Press Ltd. 2023-03 2023-03-03 /pmc/articles/PMC10011397/ /pubmed/36504117 http://dx.doi.org/10.1042/EBC20220080 Text en © 2023 The Author(s). https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article published by Portland Press Limited on behalf of the Biochemical Society and distributed under the Creative Commons Attribution License 4.0 (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Neuroscience
Roumes, Hélène
Pellerin, Luc
Bouzier-Sore, Anne-Karine
Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title_full Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title_fullStr Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title_full_unstemmed Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title_short Astrocytes as metabolic suppliers to support neuronal activity and brain functions
title_sort astrocytes as metabolic suppliers to support neuronal activity and brain functions
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011397/
https://www.ncbi.nlm.nih.gov/pubmed/36504117
http://dx.doi.org/10.1042/EBC20220080
work_keys_str_mv AT roumeshelene astrocytesasmetabolicsupplierstosupportneuronalactivityandbrainfunctions
AT pellerinluc astrocytesasmetabolicsupplierstosupportneuronalactivityandbrainfunctions
AT bouziersoreannekarine astrocytesasmetabolicsupplierstosupportneuronalactivityandbrainfunctions