Placental cell type deconvolution reveals that cell proportions drive preeclampsia gene expression differences

The placenta mediates adverse pregnancy outcomes, including preeclampsia, which is characterized by gestational hypertension and proteinuria. Placental cell type heterogeneity in preeclampsia is not well-understood and limits mechanistic interpretation of bulk gene expression measures. We generated...

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Detalles Bibliográficos
Autores principales: Campbell, Kyle A., Colacino, Justin A., Puttabyatappa, Muraly, Dou, John F., Elkin, Elana R., Hammoud, Saher S., Domino, Steven E., Dolinoy, Dana C., Goodrich, Jaclyn M., Loch-Caruso, Rita, Padmanabhan, Vasantha, Bakulski, Kelly M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011423/
https://www.ncbi.nlm.nih.gov/pubmed/36914823
http://dx.doi.org/10.1038/s42003-023-04623-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011423/
https://www.ncbi.nlm.nih.gov/pubmed/36914823
http://dx.doi.org/10.1038/s42003-023-04623-6

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