Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer’s disease

Alzheimer's disease (AD) is the most common cause of dementia. An early feature of the AD pathology is the dysregulation of intracellular Ca(2+) signaling in neurons. In particular, increased Ca(2+) release from endoplasmic reticulum-located Ca(2+) channels, including inositol-1,4,5-trisphospha...

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Detalles Bibliográficos
Autores principales: Chernyuk, D., Callens, M., Polozova, M., Gordeev, A., Chigriai, M., Rakovskaya, A., Ilina, A., Pchitskaya, E., Van den Haute, C., Vervliet, T., Bultynck, G., Bezprozvanny, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011438/
https://www.ncbi.nlm.nih.gov/pubmed/36926591
http://dx.doi.org/10.1016/j.ibneur.2023.02.005

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