Cargando…
Quantitative phosphoproteomic analysis reveals unique cAMP signaling pools emanating from AC2 and AC6 in human airway smooth muscle cells
Human airway smooth muscle (HASM) is the primary target of ßAR agonists used to control airway hypercontractility in asthma and chronic obstructive pulmonary disease (COPD). ßAR agonists induce the production of cAMP by adenylyl cyclases (ACs), activate PKA and cause bronchodilation. Several other G...
Autores principales: | Cattani-Cavalieri, Isabella, Li, Yue, Margolis, Jordyn, Bogard, Amy, Roosan, Moom R., Ostrom, Rennolds S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011497/ https://www.ncbi.nlm.nih.gov/pubmed/36926196 http://dx.doi.org/10.3389/fphys.2023.1149063 |
Ejemplares similares
-
Glucocorticoids rapidly activate cAMP production via G(αs) to initiate non‐genomic signaling that contributes to one‐third of their canonical genomic effects
por: Nuñez, Francisco J., et al.
Publicado: (2019) -
Targeting the sAC-Dependent cAMP Pool to Prevent SARS-Cov-2 Infection
por: Aslam, Muhammad, et al.
Publicado: (2020) -
Regulation of Mitochondrial Homeostasis by sAC-Derived cAMP Pool: Basic and Translational Aspects
por: Aslam, Muhammad, et al.
Publicado: (2021) -
SARS-CoV-2 early infection signature identified potential key infection mechanisms and drug targets
por: Li, Yue, et al.
Publicado: (2021) -
Sensory primary cilium is a responsive cAMP microdomain in renal epithelia
por: Sherpa, Rinzhin T., et al.
Publicado: (2019)