De novo lipogenesis fuels adipocyte autophagosome and lysosome membrane dynamics

Adipocytes robustly synthesize fatty acids (FA) from carbohydrate through the de novo lipogenesis (DNL) pathway, yet surprisingly DNL contributes little to their abundant triglyceride stored in lipid droplets. This conundrum raises the hypothesis that adipocyte DNL instead enables membrane expansion...

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Detalles Bibliográficos
Autores principales: Rowland, Leslie A., Guilherme, Adilson, Henriques, Felipe, DiMarzio, Chloe, Munroe, Sean, Wetoska, Nicole, Kelly, Mark, Reddig, Keith, Hendricks, Gregory, Pan, Meixia, Han, Xianlin, Ilkayeva, Olga R., Newgard, Christopher B., Czech, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011520/
https://www.ncbi.nlm.nih.gov/pubmed/36914626
http://dx.doi.org/10.1038/s41467-023-37016-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011520/
https://www.ncbi.nlm.nih.gov/pubmed/36914626
http://dx.doi.org/10.1038/s41467-023-37016-8

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