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Structural basis of vitamin C recognition and transport by mammalian SVCT1 transporter

Vitamin C (L-ascorbic acid) is an essential nutrient for human health, and its deficiency has long been known to cause scurvy. Sodium-dependent vitamin C transporters (SVCTs) are responsible for vitamin C uptake and tissue distribution in mammals. Here, we present cryogenic electron microscopy struc...

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Detalles Bibliográficos
Autores principales:	Wang, Mingxing, He, Jin, Li, Shanshan, Cai, Qianwen, Zhang, Kaiming, She, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011568/ https://www.ncbi.nlm.nih.gov/pubmed/36914666 http://dx.doi.org/10.1038/s41467-023-37037-3

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