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Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that induces the progression of steatosis to steatohepatitis with fibrosis in mice. Furthermore, TCDD reprograms hepatic metabolism by redirecting glycolytic intermediates while inhibiting lipid metabolism. Here, we...

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Detalles Bibliográficos
Autores principales:	Cholico, Giovan N., Orlowska, Karina, Fling, Russell R., Sink, Warren J., Zacharewski, Nicholas A., Fader, Kelly A., Nault, Rance, Zacharewski, Tim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011583/ https://www.ncbi.nlm.nih.gov/pubmed/36914879 http://dx.doi.org/10.1038/s41598-023-31087-9

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