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Towards routine chromosome-scale haplotype-resolved reconstruction in cancer genomics
Cancer genomes are highly complex and heterogeneous. The standard short-read sequencing and analytical methods are unable to provide the complete and precise base-level structural variant landscape of cancer genomes. In this work, we apply high-resolution long accurate HiFi and long-range Hi-C seque...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011606/ https://www.ncbi.nlm.nih.gov/pubmed/36914638 http://dx.doi.org/10.1038/s41467-023-36689-5 |