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A standardized extract of Coleus forskohlii root protects rats from ovariectomy-induced loss of bone mass and strength, and impaired bone material by osteogenic and anti-resorptive mechanisms

INTRODUCTION: In obese humans, Coleus forskohlii root extract (CF) protects against weight gain owing to the presence of forskolin, an adenylate cyclase (AC) activator. As AC increases intracellular cyclic adenosine monophosphate (cAMP) levels in osteoblasts that has an osteogenic effect, we thus te...

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Detalles Bibliográficos
Autores principales: Kulkarni, Chirag, Sharma, Shivani, Porwal, Konica, Rajput, Swati, Sadhukhan, Sreyanko, Singh, Vaishnavi, Singh, Akanksha, Baranwal, Sanjana, Kumar, Saroj, Girme, Aboli, Pandey, Alka Raj, Singh, Suriya Pratap, Sashidhara, Koneni V., Kumar, Navin, Hingorani, Lal, Chattopadhyay, Naibedya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011618/
https://www.ncbi.nlm.nih.gov/pubmed/36926021
http://dx.doi.org/10.3389/fendo.2023.1130003