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The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration
Rho GTPases regulate cell morphogenesis and motility under the tight control of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins (GAPs). However, the underlying mechanism(s) that coordinate their spatiotemporal activities, whether separately or together, remain unclear. We s...
Autores principales: | Wong, Darren Chen Pei, Pan, Catherine Qiurong, Er, Shi Yin, Thivakar, T., Rachel, Tan Zi Yi, Seah, Sock Hong, Chua, Pei Jou, Jiang, Tingting, Chew, Ti Weng, Chaudhuri, Parthiv Kant, Mukherjee, Somsubhro, Salim, Agus, Aye, Thike Aye, Koh, Cheng Gee, Lim, Chwee Teck, Tan, Puay Hoon, Bay, Boon Huat, Ridley, Anne J., Low, Boon Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011724/ https://www.ncbi.nlm.nih.gov/pubmed/36598812 http://dx.doi.org/10.1091/mbc.E21-03-0099 |
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