A multimodal analysis of genomic and RNA splicing features in myeloid malignancies

RNA splicing dysfunctions are more widespread than what is believed by only estimating the effects resulting by splicing factor mutations (SF(MT)) in myeloid neoplasia (MN). The genetic complexity of MN is amenable to machine learning (ML) strategies. We applied an integrative ML approach to identif...

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Detalles Bibliográficos
Autores principales: Durmaz, Arda, Gurnari, Carmelo, Hershberger, Courtney E., Pagliuca, Simona, Daniels, Noah, Awada, Hassan, Awada, Hussein, Adema, Vera, Mori, Minako, Ponvilawan, Ben, Kubota, Yasuo, Kewan, Tariq, Bahaj, Waled S., Barnard, John, Scott, Jacob, Padgett, Richard A., Haferlach, Torsten, Maciejewski, Jaroslaw P., Visconte, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011742/
https://www.ncbi.nlm.nih.gov/pubmed/36926651
http://dx.doi.org/10.1016/j.isci.2023.106238

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