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NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation

In thymus, the ablation of T cell receptor (TCR)-activated transcription factor NFATc1 or its inducible isoforms during the double-negative (DN) stages of thymocyte development leads to a marked increase in γδ thymocytes whereas the development of αβ thymocytes remains mostly unaffected. These γδ th...

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Detalles Bibliográficos
Autores principales:	Giampaolo, Sabrina, Chiarolla, Cristina M., Knöpper, Konrad, Vaeth, Martin, Klein, Matthias, Muhammad, Azeem, Bopp, Tobias, Berberich-Siebelt, Friederike, Patra, Amiya K., Serfling, Edgar, Klein-Hessling, Stefan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011748/ https://www.ncbi.nlm.nih.gov/pubmed/36926655 http://dx.doi.org/10.1016/j.isci.2023.106234

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