Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies

The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies m...

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Detalles Bibliográficos
Autor principal: Andrade, Chittaranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Learning Curve
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011845/
https://www.ncbi.nlm.nih.gov/pubmed/36925488
http://dx.doi.org/10.1177/02537176221149162
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author Andrade, Chittaranjan
author_facet Andrade, Chittaranjan
author_sort Andrade, Chittaranjan
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description The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies may be reduced so as to better detect and understand the signal. Postrandomization bias related to RCTs and confounding in observational studies are discussed. Examples are provided to facilitate understanding.
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spelling pubmed-100118452023-03-15 Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies Andrade, Chittaranjan Indian J Psychol Med Learning Curve The previous article in this series explained basic concepts related to statistical signals and statistical noise in research. This article explains statistical noise in the context of randomized controlled trials (RCTs) and observational studies and offers suggestions on how noise in such studies may be reduced so as to better detect and understand the signal. Postrandomization bias related to RCTs and confounding in observational studies are discussed. Examples are provided to facilitate understanding. SAGE Publications 2023-02-01 2023-03 /pmc/articles/PMC10011845/ /pubmed/36925488 http://dx.doi.org/10.1177/02537176221149162 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Learning Curve
Andrade, Chittaranjan
Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title_full Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title_fullStr Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title_full_unstemmed Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title_short Understanding Statistical Noise in Research: 2. Noise in Clinical Trials and Observational Studies
title_sort understanding statistical noise in research: 2. noise in clinical trials and observational studies
topic Learning Curve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10011845/
https://www.ncbi.nlm.nih.gov/pubmed/36925488
http://dx.doi.org/10.1177/02537176221149162
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