Cargando…
Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia
BACKGROUND: Evaluating the medicine burden from the patients’ perspective is essential for getting good health outcomes of diabetes mellitus (DM) management. However, data are limited regarding this sensitive area. Thus, the study was aimed to determine the medication-related burden (MRB) and associ...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012090/ https://www.ncbi.nlm.nih.gov/pubmed/36992753 http://dx.doi.org/10.3389/fcdhc.2022.977216 |
_version_ | 1784906545112285184 |
---|---|
author | Bekalu, Abaynesh Fentahun Yenit, Melaku Kindie Tekile, Masho Tigabe Birarra, Mequanent Kassa |
author_facet | Bekalu, Abaynesh Fentahun Yenit, Melaku Kindie Tekile, Masho Tigabe Birarra, Mequanent Kassa |
author_sort | Bekalu, Abaynesh Fentahun |
collection | PubMed |
description | BACKGROUND: Evaluating the medicine burden from the patients’ perspective is essential for getting good health outcomes of diabetes mellitus (DM) management. However, data are limited regarding this sensitive area. Thus, the study was aimed to determine the medication-related burden (MRB) and associated factors among DM patients at Felege Hiwot Comprehensive Specialized Hospital (FHCSH) in northwest Ethiopia. METHODS: A cross-sectional study was conducted on 423 systematically selected DM patients attending the DM clinic of FHCSH from June to August 2020. The medication-related burden was measured by using the Living with Medicines Questionnaire version 3 (LMQ-3). Multiple linear regression was used to identify factors associated with medication-related burden and reported with 95% confidence interval (CI). p-value <0.05 was considered as statistically significant to declare an association. RESULTS: The mean LMQ-3 score was 126.52 ( ± 17.39). The majority of the participants experienced moderate (58.9%, 95% CI: 53.9–63.7) to high (26.2%, 95% CI: 22.5–30.0) degrees of medication burden. Nearly half (44.9%, 95% CI: 39.9–49.7) of the participants were non-adherent to their prescribed medications. VAS score (B = 12.773, p = 0.001), ARMS score (B = 8.505, p = 0.001), and fasting blood glucose (FBS) on visit (B = 5.858, p = 0.003) were significantly associated with high medication-related burden. CONCLUSION: A significant number of patients suffered from high medication-related burden and non-adherence to long-term medicine. Therefore, multidimensional intervention to decrease MRB and to upgrade adherence is required to increase patients’ quality of life. |
format | Online Article Text |
id | pubmed-10012090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100120902023-03-28 Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia Bekalu, Abaynesh Fentahun Yenit, Melaku Kindie Tekile, Masho Tigabe Birarra, Mequanent Kassa Front Clin Diabetes Healthc Clinical Diabetes and Healthcare BACKGROUND: Evaluating the medicine burden from the patients’ perspective is essential for getting good health outcomes of diabetes mellitus (DM) management. However, data are limited regarding this sensitive area. Thus, the study was aimed to determine the medication-related burden (MRB) and associated factors among DM patients at Felege Hiwot Comprehensive Specialized Hospital (FHCSH) in northwest Ethiopia. METHODS: A cross-sectional study was conducted on 423 systematically selected DM patients attending the DM clinic of FHCSH from June to August 2020. The medication-related burden was measured by using the Living with Medicines Questionnaire version 3 (LMQ-3). Multiple linear regression was used to identify factors associated with medication-related burden and reported with 95% confidence interval (CI). p-value <0.05 was considered as statistically significant to declare an association. RESULTS: The mean LMQ-3 score was 126.52 ( ± 17.39). The majority of the participants experienced moderate (58.9%, 95% CI: 53.9–63.7) to high (26.2%, 95% CI: 22.5–30.0) degrees of medication burden. Nearly half (44.9%, 95% CI: 39.9–49.7) of the participants were non-adherent to their prescribed medications. VAS score (B = 12.773, p = 0.001), ARMS score (B = 8.505, p = 0.001), and fasting blood glucose (FBS) on visit (B = 5.858, p = 0.003) were significantly associated with high medication-related burden. CONCLUSION: A significant number of patients suffered from high medication-related burden and non-adherence to long-term medicine. Therefore, multidimensional intervention to decrease MRB and to upgrade adherence is required to increase patients’ quality of life. Frontiers Media S.A. 2022-09-09 /pmc/articles/PMC10012090/ /pubmed/36992753 http://dx.doi.org/10.3389/fcdhc.2022.977216 Text en Copyright © 2022 Bekalu, Yenit, Tekile and Birarra https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Clinical Diabetes and Healthcare Bekalu, Abaynesh Fentahun Yenit, Melaku Kindie Tekile, Masho Tigabe Birarra, Mequanent Kassa Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title | Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title_full | Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title_fullStr | Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title_full_unstemmed | Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title_short | Medication-related burden and associated factors among diabetes mellitus patients at Felege Hiwot Comprehensive Specialized Hospital in northwest Ethiopia |
title_sort | medication-related burden and associated factors among diabetes mellitus patients at felege hiwot comprehensive specialized hospital in northwest ethiopia |
topic | Clinical Diabetes and Healthcare |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012090/ https://www.ncbi.nlm.nih.gov/pubmed/36992753 http://dx.doi.org/10.3389/fcdhc.2022.977216 |
work_keys_str_mv | AT bekaluabayneshfentahun medicationrelatedburdenandassociatedfactorsamongdiabetesmellituspatientsatfelegehiwotcomprehensivespecializedhospitalinnorthwestethiopia AT yenitmelakukindie medicationrelatedburdenandassociatedfactorsamongdiabetesmellituspatientsatfelegehiwotcomprehensivespecializedhospitalinnorthwestethiopia AT tekilemashotigabe medicationrelatedburdenandassociatedfactorsamongdiabetesmellituspatientsatfelegehiwotcomprehensivespecializedhospitalinnorthwestethiopia AT birarramequanentkassa medicationrelatedburdenandassociatedfactorsamongdiabetesmellituspatientsatfelegehiwotcomprehensivespecializedhospitalinnorthwestethiopia |