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Worsening glycemic control in youth with type 2 diabetes during COVID-19

INTRODUCTION: The COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this s...

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Autores principales: Bharill, Sonum, Lin, Tyger, Arking, Alexander, Brown, Elizabeth A., West, Margaret, Busin, Kelly, Magge, Sheela N., Wolf, Risa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012097/
https://www.ncbi.nlm.nih.gov/pubmed/36992756
http://dx.doi.org/10.3389/fcdhc.2022.968113
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author Bharill, Sonum
Lin, Tyger
Arking, Alexander
Brown, Elizabeth A.
West, Margaret
Busin, Kelly
Magge, Sheela N.
Wolf, Risa M.
author_facet Bharill, Sonum
Lin, Tyger
Arking, Alexander
Brown, Elizabeth A.
West, Margaret
Busin, Kelly
Magge, Sheela N.
Wolf, Risa M.
author_sort Bharill, Sonum
collection PubMed
description INTRODUCTION: The COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this study was to evaluate weight trends and glycemic control in youth with existing T2D during the COVID-19 pandemic. METHODS: A retrospective study of youth <21 years of age diagnosed with T2D prior to March 11, 2020 was conducted at an academic pediatric diabetes center to compare glycemic control, weight, and BMI in the year prior to the COVID-19 pandemic (March 2019-2020) to during COVID-19 (March 2020-2021). Paired t-tests and linear mixed effects models were used to analyze changes during this period. RESULTS: A total of 63 youth with T2D were included (median age 15.0 (IQR 14-16) years, 59% female, 74.6% black, 14.3% Hispanic, 77.8% with Medicaid insurance). Median duration of diabetes was 0.8 (IQR 0.2-2.0) years. There was no difference in weight or BMI from the pre-COVID-19 period compared to during COVID-19 (Weight: 101.5 v 102.9 kg, p=0.18; BMI: 36.0 v 36.1 kg/m2, p=0.72). Hemoglobin A1c significantly increased during COVID-19 (7.6% vs 8.6%, p=0.0002) CONCLUSION: While hemoglobin A1c increased significantly in youth with T2D during the COVID-19 pandemic, there was no significant change in weight or BMI possibly due to glucosuria associated with hyperglycemia. Youth with T2D are at high risk for diabetes complications, and the worsening glycemic control in this population highlights the need to prioritize close follow-up and disease management to prevent further metabolic decompensation.
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spelling pubmed-100120972023-03-28 Worsening glycemic control in youth with type 2 diabetes during COVID-19 Bharill, Sonum Lin, Tyger Arking, Alexander Brown, Elizabeth A. West, Margaret Busin, Kelly Magge, Sheela N. Wolf, Risa M. Front Clin Diabetes Healthc Clinical Diabetes and Healthcare INTRODUCTION: The COVID-19 pandemic has disproportionately affected minority and lower socioeconomic populations, who also have higher rates of type 2 diabetes (T2D). The impact of virtual school, decreased activity level, and worsening food insecurity on pediatric T2D is unknown. The goal of this study was to evaluate weight trends and glycemic control in youth with existing T2D during the COVID-19 pandemic. METHODS: A retrospective study of youth <21 years of age diagnosed with T2D prior to March 11, 2020 was conducted at an academic pediatric diabetes center to compare glycemic control, weight, and BMI in the year prior to the COVID-19 pandemic (March 2019-2020) to during COVID-19 (March 2020-2021). Paired t-tests and linear mixed effects models were used to analyze changes during this period. RESULTS: A total of 63 youth with T2D were included (median age 15.0 (IQR 14-16) years, 59% female, 74.6% black, 14.3% Hispanic, 77.8% with Medicaid insurance). Median duration of diabetes was 0.8 (IQR 0.2-2.0) years. There was no difference in weight or BMI from the pre-COVID-19 period compared to during COVID-19 (Weight: 101.5 v 102.9 kg, p=0.18; BMI: 36.0 v 36.1 kg/m2, p=0.72). Hemoglobin A1c significantly increased during COVID-19 (7.6% vs 8.6%, p=0.0002) CONCLUSION: While hemoglobin A1c increased significantly in youth with T2D during the COVID-19 pandemic, there was no significant change in weight or BMI possibly due to glucosuria associated with hyperglycemia. Youth with T2D are at high risk for diabetes complications, and the worsening glycemic control in this population highlights the need to prioritize close follow-up and disease management to prevent further metabolic decompensation. Frontiers Media S.A. 2022-09-09 /pmc/articles/PMC10012097/ /pubmed/36992756 http://dx.doi.org/10.3389/fcdhc.2022.968113 Text en Copyright © 2022 Bharill, Lin, Arking, Brown, West, Busin, Magge and Wolf https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Clinical Diabetes and Healthcare
Bharill, Sonum
Lin, Tyger
Arking, Alexander
Brown, Elizabeth A.
West, Margaret
Busin, Kelly
Magge, Sheela N.
Wolf, Risa M.
Worsening glycemic control in youth with type 2 diabetes during COVID-19
title Worsening glycemic control in youth with type 2 diabetes during COVID-19
title_full Worsening glycemic control in youth with type 2 diabetes during COVID-19
title_fullStr Worsening glycemic control in youth with type 2 diabetes during COVID-19
title_full_unstemmed Worsening glycemic control in youth with type 2 diabetes during COVID-19
title_short Worsening glycemic control in youth with type 2 diabetes during COVID-19
title_sort worsening glycemic control in youth with type 2 diabetes during covid-19
topic Clinical Diabetes and Healthcare
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012097/
https://www.ncbi.nlm.nih.gov/pubmed/36992756
http://dx.doi.org/10.3389/fcdhc.2022.968113
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