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Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery

OBJECTIVE: Lumbar cistern blockage is a common complication of continuous lumbar cistern drainage. This paper analyzes the risk factors for lumbar cistern blockage drainage due to various causes and proposes a series of prevention and intervention measures to reduce blockage or improve recanalizatio...

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Autores principales: Zheng, Min, Tian, Qilong, Wang, Xuejiao, Liu, Liqin, Deng, Xiurui, Qu, Yan, Cai, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012248/
https://www.ncbi.nlm.nih.gov/pubmed/36925741
http://dx.doi.org/10.3389/fnins.2023.1124395
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author Zheng, Min
Tian, Qilong
Wang, Xuejiao
Liu, Liqin
Deng, Xiurui
Qu, Yan
Cai, Qing
author_facet Zheng, Min
Tian, Qilong
Wang, Xuejiao
Liu, Liqin
Deng, Xiurui
Qu, Yan
Cai, Qing
author_sort Zheng, Min
collection PubMed
description OBJECTIVE: Lumbar cistern blockage is a common complication of continuous lumbar cistern drainage. This paper analyzes the risk factors for lumbar cistern blockage drainage due to various causes and proposes a series of prevention and intervention measures to reduce blockage or improve recanalization after blockage. METHODS: The clinical data of 637 patients with various lesions who underwent lumbar cistern drainage in our hospital were retrospectively collected and analyzed. Perioperative clinical and imaging data were assessed. Variates were analyzed using univariate and multivariate logistic regression analyses. RESULTS: A total of 13.7% (87/637) of patients had lumbar cistern blockage. Multivariate analysis revealed that drainage time (≥7 days), CSF volume <200 (mL/d), CSF leakage, and abnormal CSF properties were predictors of lumbar cistern blockage. Reducing the probability of lumbar cistern blockage can be achieved by repeatedly flushing, increasing the drainage flow and shortening the drainage time. The recanalization rate after blockage was 67.8% (59/87). After the drainage tube was removed, no complications related to the drainage tube occurred during the 1-week follow-up. CONCLUSION: Lumbar cistern blockage is the main reason for poor drainage. Prevention or early intervention can effectively reduce the probability of blockage and achieve the purpose of drainage of cerebrospinal fluid.
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spelling pubmed-100122482023-03-15 Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery Zheng, Min Tian, Qilong Wang, Xuejiao Liu, Liqin Deng, Xiurui Qu, Yan Cai, Qing Front Neurosci Neuroscience OBJECTIVE: Lumbar cistern blockage is a common complication of continuous lumbar cistern drainage. This paper analyzes the risk factors for lumbar cistern blockage drainage due to various causes and proposes a series of prevention and intervention measures to reduce blockage or improve recanalization after blockage. METHODS: The clinical data of 637 patients with various lesions who underwent lumbar cistern drainage in our hospital were retrospectively collected and analyzed. Perioperative clinical and imaging data were assessed. Variates were analyzed using univariate and multivariate logistic regression analyses. RESULTS: A total of 13.7% (87/637) of patients had lumbar cistern blockage. Multivariate analysis revealed that drainage time (≥7 days), CSF volume <200 (mL/d), CSF leakage, and abnormal CSF properties were predictors of lumbar cistern blockage. Reducing the probability of lumbar cistern blockage can be achieved by repeatedly flushing, increasing the drainage flow and shortening the drainage time. The recanalization rate after blockage was 67.8% (59/87). After the drainage tube was removed, no complications related to the drainage tube occurred during the 1-week follow-up. CONCLUSION: Lumbar cistern blockage is the main reason for poor drainage. Prevention or early intervention can effectively reduce the probability of blockage and achieve the purpose of drainage of cerebrospinal fluid. Frontiers Media S.A. 2023-02-28 /pmc/articles/PMC10012248/ /pubmed/36925741 http://dx.doi.org/10.3389/fnins.2023.1124395 Text en Copyright © 2023 Zheng, Tian, Wang, Liu, Deng, Qu and Cai. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Zheng, Min
Tian, Qilong
Wang, Xuejiao
Liu, Liqin
Deng, Xiurui
Qu, Yan
Cai, Qing
Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title_full Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title_fullStr Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title_full_unstemmed Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title_short Analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
title_sort analysis of risk factors and treatment strategies for lumbar cistern blockage after craniocerebral surgery
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012248/
https://www.ncbi.nlm.nih.gov/pubmed/36925741
http://dx.doi.org/10.3389/fnins.2023.1124395
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