Salivary Antimicrobial Peptide Histatin-5 Does Not Display Zn(II)-Dependent or -Independent Activity against Streptococci

[Image: see text] Histatin-5 (Hst5) is a member of the histatin superfamily of cationic, His-rich, Zn(II)-binding peptides in human saliva. Hst5 displays antimicrobial activity against fungal and bacterial pathogens, often in a Zn(II)-dependent manner. In contrast, here we showed that under in vitro...

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Detalles Bibliográficos
Autores principales: Stewart, Louisa J., Hong, YoungJin, Holmes, Isabel R., Firth, Samantha J., Ahmed, Yasmin, Quinn, Janet, Santos, Yazmin, Cobb, Steven L., Jakubovics, Nicholas S., Djoko, Karrera Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012264/
https://www.ncbi.nlm.nih.gov/pubmed/36826226
http://dx.doi.org/10.1021/acsinfecdis.2c00578

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