Label-Free Mass Spectrometry Proteomics Reveals Different Pathways Modulated in THP-1 Cells Infected with Therapeutic Failure and Drug Resistance Leishmania infantum Clinical Isolates

[Image: see text] As the world is facing increasing difficulties to treat leishmaniasis with current therapies, deeper investigation into the molecular mechanisms responsible for both drug resistance and treatment failure (TF) is essential in drug discovery and development. So far, few available dru...

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Autores principales: Tagliazucchi, Lorenzo, Perea-Martinez, Ana, Fiorini, Greta, Manzano, José Ignacio, Genovese, Filippo, García-Hernández, Raquel, Pinetti, Diego, Gamarro, Francisco, Costi, Maria Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012269/
https://www.ncbi.nlm.nih.gov/pubmed/36762976
http://dx.doi.org/10.1021/acsinfecdis.2c00457

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