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In Vitro and In Vivo Development of a β-Lactam-Metallo-β-Lactamase Inhibitor: Targeting Carbapenem-Resistant Enterobacterales

[Image: see text] β-lactams are the most prescribed class of antibiotics due to their potent, broad-spectrum antimicrobial activities. However, alarming rates of antimicrobial resistance now threaten the clinical relevance of these drugs, especially for the carbapenem-resistant Enterobacterales expr...

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Detalles Bibliográficos
Autores principales:	Peters, Byron K., Reddy, Nakita, Shungube, Mbongeni, Girdhari, Letisha, Baijnath, Sooraj, Mdanda, Sipho, Chetty, Lloyd, Ntombela, Thandokuhle, Arumugam, Thilona, Bester, Linda A., Singh, Sanil D., Chuturgoon, Anil, Arvidsson, Per I., Maguire, Glenn E. M., Kruger, Hendrik G., Naicker, Tricia, Govender, Thavendran
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012271/ https://www.ncbi.nlm.nih.gov/pubmed/36786013 http://dx.doi.org/10.1021/acsinfecdis.2c00485

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