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In Vivo Injection of Anti-LGI1 Antibodies into the Rodent M1 Cortex and Hippocampus Is Ineffective in Inducing Seizures

Autoimmune encephalitis (AIE) associated with antibodies directed against the leucine-rich glioma inactivated 1 (LGI1) protein is the second most common AIE and is responsible for deleterious neocortical and limbic epileptic seizures. Previous studies demonstrated a pathogenic role of anti-LGI1 anti...

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Detalles Bibliográficos
Autores principales: Baudin, Paul, Roussel, Delphine, Mahon, Séverine, Charpier, Stéphane, Navarro, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012326/
https://www.ncbi.nlm.nih.gov/pubmed/36849262
http://dx.doi.org/10.1523/ENEURO.0267-22.2023