Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by stabilizing IκBα

Spinal cord injury (SCI) can result in irreversible sensory and motor disability with no effective treatment currently. After SCI, infiltrated macrophages accumulate in epicenter through destructed blood-spinal cord barrier (BSCB). Further, great majority of macrophages are preferentially polarized...

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Detalles Bibliográficos
Autores principales: Ge, Xuhui, Zhou, Zheng, Yang, Siting, Ye, Wu, Wang, Zhuanghui, Wang, Jiaxing, Xiao, Chenyu, Cui, Min, Zhou, Jiawen, Zhu, Yufeng, Wang, Rixiao, Gao, Yu, Wang, Haofan, Tang, Pengyu, Zhou, Xuhui, Wang, Ce, Cai, Weihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012460/
https://www.ncbi.nlm.nih.gov/pubmed/36915206
http://dx.doi.org/10.1186/s13578-023-01011-9

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