LINP1 represses unfolded protein response by directly inhibiting eIF2α phosphorylation to promote cutaneous squamous cell carcinoma

BACKGROUND: Endoplasmic reticulum stress (ER stress) may destroy endoplasmic reticulum homeostasis (ER homeostasis) and leads to programmable cell death. Unfolded protein response (UPR) originally stimulated by ER stress is critical for the survival of tumor cells through trying to re-establish ER h...

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Detalles Bibliográficos
Autores principales: Liang, Xiaoting, Liu, Jieyu, Liu, Xingyuan, Jin, Yi, Xu, Minna, Han, Zhenyu, Wang, Ke, Zhang, Chunting, Zou, Fei, Zhou, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012465/
https://www.ncbi.nlm.nih.gov/pubmed/36918934
http://dx.doi.org/10.1186/s40164-023-00395-1

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