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Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice

BACKGROUND: Bushenhuoxue (BSHX) formula, a ten-compound herbal decoction, is widely used to treat postmenopausal osteoporosis (PMOP) in China. However, the mechanism is not clear yet. METHODS: The underlying biological processes and signaling pathways were predicted by network pharmacology. In vivo...

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Detalles Bibliográficos
Autores principales: Xia, Chenjie, Zhu, Haowei, Li, Jin, Jin, Hongting, Fu, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012505/
https://www.ncbi.nlm.nih.gov/pubmed/36918900
http://dx.doi.org/10.1186/s13018-023-03696-7