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Network pharmacology-based mechanism prediction and pharmacological validation of Bushenhuoxue formula attenuating postmenopausal osteoporosis in ovariectomized mice
BACKGROUND: Bushenhuoxue (BSHX) formula, a ten-compound herbal decoction, is widely used to treat postmenopausal osteoporosis (PMOP) in China. However, the mechanism is not clear yet. METHODS: The underlying biological processes and signaling pathways were predicted by network pharmacology. In vivo...
Autores principales: | Xia, Chenjie, Zhu, Haowei, Li, Jin, Jin, Hongting, Fu, Danqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012505/ https://www.ncbi.nlm.nih.gov/pubmed/36918900 http://dx.doi.org/10.1186/s13018-023-03696-7 |
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