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Enhancement of herbicolin A production by integrated fermentation optimization and strain engineering in Pantoea agglomerans ZJU23

BACKGROUND: The lipopeptide herbicolin A (HA) secreted by the biocontrol agent Pantoea agglomerans ZJU23 is a promising antifungal drug to combat fungal pathogens by targeting lipid rafts, both in agricultural and clinical settings. Improvement of HA production would be of great significance in prom...

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Detalles Bibliográficos
Autores principales: Wang, Hongkai, Zhou, Yaqi, Xu, Sunde, Zhang, Boyan, Cernava, Tomislav, Ma, Zhonghua, Chen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012537/
https://www.ncbi.nlm.nih.gov/pubmed/36915090
http://dx.doi.org/10.1186/s12934-023-02051-z