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Changes in CSF sPDGFRβ level and their association with blood–brain barrier breakdown in Alzheimer’s disease with or without small cerebrovascular lesions

BACKGROUND: CSF-soluble platelet-derived growth factor receptor beta (sPDGFRβ) is closely associated with pericyte damage. However, the changes in CSF sPDGFRβ levels and their role in blood–brain barrier (BBB) leakage at different stages of Alzheimer’s disease (AD), with or without cerebral small ve...

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Detalles Bibliográficos
Autores principales: Lv, Xinyi, Zhang, Mengguo, Cheng, Zhaozhao, Wang, Qiong, Wang, Peng, Xie, Qiang, Ni, Ming, Shen, Yong, Tang, Qiqiang, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012584/
https://www.ncbi.nlm.nih.gov/pubmed/36915135
http://dx.doi.org/10.1186/s13195-023-01199-5