Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system

BACKGROUND: ε-Poly-L-lysine (ε-PL) is a natural and safe food preservative that is mainly produced by filamentous and aerobic bacteria Streptomyces albulus. During ε-PL biosynthesis, a large amount of ATP is used for the polymerization of L-lysine. A shortage of intracellular ATP is one of the major...

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Detalles Bibliográficos
Autores principales: Yang, Hao, Zhu, Daojun, Kai, Lang, Wang, Liang, Zhang, Hongjian, Zhang, Jianhua, Chen, Xusheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012588/
https://www.ncbi.nlm.nih.gov/pubmed/36918890
http://dx.doi.org/10.1186/s12934-023-02057-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012588/
https://www.ncbi.nlm.nih.gov/pubmed/36918890
http://dx.doi.org/10.1186/s12934-023-02057-7

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