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Engineering Streptomyces albulus to enhance ε-poly-L-lysine production by introducing a polyphosphate kinase-mediated ATP regeneration system

BACKGROUND: ε-Poly-L-lysine (ε-PL) is a natural and safe food preservative that is mainly produced by filamentous and aerobic bacteria Streptomyces albulus. During ε-PL biosynthesis, a large amount of ATP is used for the polymerization of L-lysine. A shortage of intracellular ATP is one of the major...

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Detalles Bibliográficos
Autores principales:	Yang, Hao, Zhu, Daojun, Kai, Lang, Wang, Liang, Zhang, Hongjian, Zhang, Jianhua, Chen, Xusheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012588/ https://www.ncbi.nlm.nih.gov/pubmed/36918890 http://dx.doi.org/10.1186/s12934-023-02057-7

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