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Are standing osmotic gradients the main driver of cerebrospinal fluid production? A computational analysis

BACKGROUND: The mechanisms of cerebrospinal fluid (CSF) production by the ventricular choroid plexus (ChP) have not been fully deciphered. One prominent hypothesized mechanism is trans-epithelial water transport mediated by accumulation of solutes at the luminal ChP membrane that produces local osmo...

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Detalles Bibliográficos
Autores principales: Razzaghi Khamesi, Pooya, Charitatos, Vasileios, Heerfordt, Eva K., MacAulay, Nanna, Kurtcuoglu, Vartan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012606/
https://www.ncbi.nlm.nih.gov/pubmed/36915140
http://dx.doi.org/10.1186/s12987-023-00419-2