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Functional nano-systems for transdermal drug delivery and skin therapy
Transdermal drug delivery is one of the least intrusive and patient-friendly ways for therapeutic agent administration. Recently, functional nano-systems have been demonstrated as one of the most promising strategies to treat skin diseases by improving drug penetration across the skin barrier and ac...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
RSC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012846/ https://www.ncbi.nlm.nih.gov/pubmed/36926556 http://dx.doi.org/10.1039/d2na00530a |
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author | Liu, Lijun Zhao, Wenbin Ma, Qingming Gao, Yang Wang, Weijiang Zhang, Xuan Dong, Yunxia Zhang, Tingting Liang, Yan Han, Shangcong Cao, Jie Wang, Xinyu Sun, Wentao Ma, Haifeng Sun, Yong |
author_facet | Liu, Lijun Zhao, Wenbin Ma, Qingming Gao, Yang Wang, Weijiang Zhang, Xuan Dong, Yunxia Zhang, Tingting Liang, Yan Han, Shangcong Cao, Jie Wang, Xinyu Sun, Wentao Ma, Haifeng Sun, Yong |
author_sort | Liu, Lijun |
collection | PubMed |
description | Transdermal drug delivery is one of the least intrusive and patient-friendly ways for therapeutic agent administration. Recently, functional nano-systems have been demonstrated as one of the most promising strategies to treat skin diseases by improving drug penetration across the skin barrier and achieving therapeutically effective drug concentrations in the target cutaneous tissues. Here, a brief review of functional nano-systems for promoting transdermal drug delivery is presented. The fundamentals of transdermal delivery, including skin biology and penetration routes, are introduced. The characteristics of functional nano-systems for facilitating transdermal drug delivery are elucidated. Moreover, the fabrication of various types of functional transdermal nano-systems is systematically presented. Multiple techniques for evaluating the transdermal capacities of nano-systems are illustrated. Finally, the advances in the applications of functional transdermal nano-systems for treating different skin diseases are summarized. |
format | Online Article Text |
id | pubmed-10012846 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | RSC |
record_format | MEDLINE/PubMed |
spelling | pubmed-100128462023-03-15 Functional nano-systems for transdermal drug delivery and skin therapy Liu, Lijun Zhao, Wenbin Ma, Qingming Gao, Yang Wang, Weijiang Zhang, Xuan Dong, Yunxia Zhang, Tingting Liang, Yan Han, Shangcong Cao, Jie Wang, Xinyu Sun, Wentao Ma, Haifeng Sun, Yong Nanoscale Adv Chemistry Transdermal drug delivery is one of the least intrusive and patient-friendly ways for therapeutic agent administration. Recently, functional nano-systems have been demonstrated as one of the most promising strategies to treat skin diseases by improving drug penetration across the skin barrier and achieving therapeutically effective drug concentrations in the target cutaneous tissues. Here, a brief review of functional nano-systems for promoting transdermal drug delivery is presented. The fundamentals of transdermal delivery, including skin biology and penetration routes, are introduced. The characteristics of functional nano-systems for facilitating transdermal drug delivery are elucidated. Moreover, the fabrication of various types of functional transdermal nano-systems is systematically presented. Multiple techniques for evaluating the transdermal capacities of nano-systems are illustrated. Finally, the advances in the applications of functional transdermal nano-systems for treating different skin diseases are summarized. RSC 2023-02-24 /pmc/articles/PMC10012846/ /pubmed/36926556 http://dx.doi.org/10.1039/d2na00530a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Liu, Lijun Zhao, Wenbin Ma, Qingming Gao, Yang Wang, Weijiang Zhang, Xuan Dong, Yunxia Zhang, Tingting Liang, Yan Han, Shangcong Cao, Jie Wang, Xinyu Sun, Wentao Ma, Haifeng Sun, Yong Functional nano-systems for transdermal drug delivery and skin therapy |
title | Functional nano-systems for transdermal drug delivery and skin therapy |
title_full | Functional nano-systems for transdermal drug delivery and skin therapy |
title_fullStr | Functional nano-systems for transdermal drug delivery and skin therapy |
title_full_unstemmed | Functional nano-systems for transdermal drug delivery and skin therapy |
title_short | Functional nano-systems for transdermal drug delivery and skin therapy |
title_sort | functional nano-systems for transdermal drug delivery and skin therapy |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012846/ https://www.ncbi.nlm.nih.gov/pubmed/36926556 http://dx.doi.org/10.1039/d2na00530a |
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