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Design of self-assembled glycopolymeric zwitterionic micelles as removable protein stabilizing agents
Developing stabilizers that protect proteins from denaturation under stress, and are easy to remove from solutions, is a challenge in protein therapeutics. In this study, micelles made of trehalose, a zwitterionic polymer (poly-sulfobetaine; poly-SPB), and polycaprolactone (PCL) were synthesized by...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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RSC
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10012880/ https://www.ncbi.nlm.nih.gov/pubmed/36926568 http://dx.doi.org/10.1039/d3na00002h |