Distinct IDH1/2-associated Methylation Profile and Enrichment of TP53 and TERT Mutations Distinguish Dedifferentiated Chondrosarcoma from Conventional Chondrosarcoma

Dedifferentiated chondrosarcoma (DDCS) is a rare high-grade chondrosarcoma characterized by a well-differentiated chondrosarcoma (WDCS) component that abruptly transitions to a high-grade, noncartilaginous sarcomatous component. To date, the molecular pathogenesis of DDCS and its distinction from co...

Descripción completa

Detalles Bibliográficos
Autores principales: Dermawan, Josephine Kam Tai, Nafa, Khedoujia, Mohanty, Abhinita, Xu, Yingjuan, Rijo, Ivelise, Casanova, Jacklyn, Villafania, Liliana, Benhamida, Jamal, Kelly, Ciara M., Tap, William D., Boland, Patrick J., Fabbri, Nicola, Healey, John H., Ladanyi, Marc, Lu, Chao, Hameed, Meera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013202/
https://www.ncbi.nlm.nih.gov/pubmed/36926116
http://dx.doi.org/10.1158/2767-9764.CRC-22-0397

Ejemplares similares

Ejemplares similares