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WRH-2412 alleviates the progression of hepatocellular carcinoma through regulation of TGF-β/β-catenin/α-SMA pathway

Hepatocellular carcinoma is considered one of the most lethal cancers, which is characterised by increasing prevalence associated with high level of invasion and metastasis. The novel synthetic pyrazolo[3,4-b]pyridine compound, WRH-2412, was reported to exhibit in vitro antitumor activity. This stud...

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Detalles Bibliográficos
Autores principales: Elewa, Mohammed A. F., Eldehna, Wagdy M., Hamdan, Ahmed M. E., Abd El-kawi, Samraa H., El-Kalaawy, Asmaa M., Majrashi, Taghreed A., Barghash, Reham F., Abdel-Aziz, Hatem A., Hashem, Khalid S., Al-Gayyar, Mohammed M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013371/
https://www.ncbi.nlm.nih.gov/pubmed/36912230
http://dx.doi.org/10.1080/14756366.2023.2185761