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Optimizing the order of actions in a model of contact tracing
Contact tracing is a key tool for managing epidemic diseases like HIV, tuberculosis, COVID-19, and monkeypox. Manual investigations by human-contact tracers remain a dominant way in which this is carried out. This process is limited by the number of contact tracers available, who are often overburde...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013731/ https://www.ncbi.nlm.nih.gov/pubmed/36926225 http://dx.doi.org/10.1093/pnasnexus/pgad003 |
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author | Meister, Michela Kleinberg, Jon |
author_facet | Meister, Michela Kleinberg, Jon |
author_sort | Meister, Michela |
collection | PubMed |
description | Contact tracing is a key tool for managing epidemic diseases like HIV, tuberculosis, COVID-19, and monkeypox. Manual investigations by human-contact tracers remain a dominant way in which this is carried out. This process is limited by the number of contact tracers available, who are often overburdened during an outbreak or epidemic. As a result, a crucial decision in any contact tracing strategy is, given a set of contacts, which person should a tracer trace next? In this work, we develop a formal model that articulates these questions and provides a framework for comparing contact tracing strategies. Through analyzing our model, we give provably optimal prioritization policies via a clean connection to a tool from operations research called a “branching bandit”. Examining these policies gives qualitative insight into trade-offs in contact tracing applications. |
format | Online Article Text |
id | pubmed-10013731 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-100137312023-03-15 Optimizing the order of actions in a model of contact tracing Meister, Michela Kleinberg, Jon PNAS Nexus Physical Sciences and Engineering Contact tracing is a key tool for managing epidemic diseases like HIV, tuberculosis, COVID-19, and monkeypox. Manual investigations by human-contact tracers remain a dominant way in which this is carried out. This process is limited by the number of contact tracers available, who are often overburdened during an outbreak or epidemic. As a result, a crucial decision in any contact tracing strategy is, given a set of contacts, which person should a tracer trace next? In this work, we develop a formal model that articulates these questions and provides a framework for comparing contact tracing strategies. Through analyzing our model, we give provably optimal prioritization policies via a clean connection to a tool from operations research called a “branching bandit”. Examining these policies gives qualitative insight into trade-offs in contact tracing applications. Oxford University Press 2023-01-20 /pmc/articles/PMC10013731/ /pubmed/36926225 http://dx.doi.org/10.1093/pnasnexus/pgad003 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of National Academy of Sciences. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Physical Sciences and Engineering Meister, Michela Kleinberg, Jon Optimizing the order of actions in a model of contact tracing |
title | Optimizing the order of actions in a model of contact tracing |
title_full | Optimizing the order of actions in a model of contact tracing |
title_fullStr | Optimizing the order of actions in a model of contact tracing |
title_full_unstemmed | Optimizing the order of actions in a model of contact tracing |
title_short | Optimizing the order of actions in a model of contact tracing |
title_sort | optimizing the order of actions in a model of contact tracing |
topic | Physical Sciences and Engineering |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013731/ https://www.ncbi.nlm.nih.gov/pubmed/36926225 http://dx.doi.org/10.1093/pnasnexus/pgad003 |
work_keys_str_mv | AT meistermichela optimizingtheorderofactionsinamodelofcontacttracing AT kleinbergjon optimizingtheorderofactionsinamodelofcontacttracing |