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Innate immune cell activation causes lung fibrosis in a humanized model of long COVID

COVID-19 remains a global pandemic of an unprecedented magnitude with millions of people now developing “COVID lung fibrosis.” Single-cell transcriptomics of lungs of patients with long COVID revealed a unique immune signature demonstrating the upregulation of key proinflammatory and innate immune e...

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Detalles Bibliográficos
Autores principales: Cui, Lu, Fang, Zhuoqing, De Souza, Cristabelle Madona, Lerbs, Tristan, Guan, Yuan, Li, Irene, Charu, Vivek, Chen, Shih-Yu, Weissman, Irving, Wernig, Gerlinde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10013740/
https://www.ncbi.nlm.nih.gov/pubmed/36848564
http://dx.doi.org/10.1073/pnas.2217199120